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Charting the Course: Towards a Comprehensive Newborn Screening Program in India.

Seema Kapoor1, Amit Kumar Gupta1, B K Thelma2

  • 1Genetic & Metabolic Lab, Division of Genetics, Department of Pediatrics, Lok Nayak Hospital & Maulana Azad Medical College, New Delhi 110002, India.

International Journal of Neonatal Screening
|July 25, 2024
PubMed
Summary
This summary is machine-generated.

Newborn screening (NBS) in India is crucial for preventing metabolic disorders. A feasibility study in Delhi highlighted key factors like data, training, public awareness, and national policy for successful universal NBS implementation.

Keywords:
Delhi Stateinborn errors of metabolismlow- and middle-income countriesnewborn screening programpublic health

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Area of Science:

  • Public Health
  • Neonatal Medicine
  • Genetics

Background:

  • India faces challenges in integrating health interventions due to its large birth cohort and high neonatal mortality rate.
  • While mortality data exists, intact survival through early preventive healthcare like newborn screening (NBS) is critical.
  • A lack of national data on metabolic errors and a mandated NBS program prompted a feasibility study.

Purpose of the Study:

  • To assess the feasibility of implementing newborn screening (NBS) in India.
  • To identify determinants and limitations for a universal NBS program.
  • To inform national policy for early detection of metabolic errors.

Main Methods:

  • A prospective newborn cohort was recruited in Delhi State from November 2014 to April 2017.
  • The study utilized a public-private partnership model for implementation.
  • Data analysis focused on identifying requirements for a national NBS program.

Main Results:

  • The study identified critical needs for effective universal NBS implementation.
  • Key requirements include comprehensive screening data, sustained healthcare personnel training, and public awareness campaigns.
  • A national policy framework is essential for successful integration.

Conclusions:

  • Implementing universal newborn screening in India requires strategic planning and resource allocation.
  • Addressing data gaps, training needs, public engagement, and policy development are priorities.
  • Successful NBS can significantly improve neonatal and societal health outcomes in India.