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Updated: Jun 19, 2025

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
Published on: February 13, 2018
Leprous neuropathy
1School of Medicine of Ribeirão Preto, University of São Paulo Department of Neurosciences and Behavior Sciences, Ribeirão Preto, SP, Brazil.
Purpose Of Review:
Leprosy is still an important cause of neuropathy. Late diagnosis is associated with development of severe nerve impairment.
Recent Findings:
early diagnosis and early treatment is essential in order to avoid disability and disease transmission. Recognizing that leprosy is a neurological disease is a fundamental step to the Leprosy zero action proposed by the World Health Organization.
Summary:
leprosy neuropathy manifests as a mononeuropathy or a multiple mononeuropathy with a temperature-dependent distribution. Electromyography, high-resolution sonography serology and PCR help make the diagnosis. Multidrug therapy should be instituted.
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