Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

406
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
406

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world treatment patterns and determinants of therapy in systemic sclerosis: findings from the German Network for SSc cohort.

Arthritis research & therapy·2026
Same author

Csf1r-mediated depletion of myeloid cells prevents dopaminergic neuron loss during chronic colitis.

Journal of neuroinflammation·2026
Same author

BCMA-directed therapy with cizutamig induces rapid improvement in long-standing systemic sclerosis-associated interstitial lung disease.

Rheumatology (Oxford, England)·2026
Same author

Teclistamab for treatment-refractory autoimmune diseases: a multicentre case series.

Annals of the rheumatic diseases·2026
Same author

Teclistamab induces rapid clinical response and deep tissue depletion in refractory systemic sclerosis-a case series.

Annals of the rheumatic diseases·2026
Same author

In vitro modeling of inflammatory bowel diseases using a newly developed immunocompetent colon epithelial monolayer co-culture model.

npj biomedical innovations·2026

Related Experiment Video

Updated: Jun 19, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

7.1K

[Interdisciplinary centers for autoimmune diseases in Germany].

Margitta Worm1, Claudia Günther2, Martin Claussen3

  • 1Abteilung für Allergologie und Immunologie, Klinik für Dermatologie, Venerologie und Allergologie, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. margitta.worm@charite.de.

Zeitschrift Fur Rheumatologie
|July 25, 2024
PubMed
Summary

Interdisciplinary centers for autoimmune diseases require standardized procedures for optimal patient care. Establishing national consensus is crucial for consistent, adaptable treatment across Germany.

Keywords:
GuidelinesMedical specialist careStandard of careSystemic sclerosis

More Related Videos

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.3K
Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
05:34

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

586

Related Experiment Videos

Last Updated: Jun 19, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

7.1K
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.3K
Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
05:34

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

586

Area of Science:

  • Rheumatology and Immunology
  • Healthcare Management
  • Clinical Medicine

Context:

  • Complex autoimmune diseases necessitate interdisciplinary medical treatment.
  • Germany has a growing number of interdisciplinary centers for autoimmune diseases, but lacks national standardization in structure and focus.
  • Existing centers are not consistently integrated into the general healthcare system.

Purpose:

  • To analyze the current care structure of interdisciplinary autoimmune disease centers in Germany.
  • To demonstrate the utility of standardized operating procedures (SOPs) through a clinical case example.
  • To advocate for a national consensus on the structure and implementation of such centers.

Summary:

  • An exemplary university hospital center provides interdisciplinary care for autoimmune disease patients, with structures integrated into its organizational chart.
  • A case report illustrates a standardized diagnostic and therapeutic pathway for systemic sclerosis with lung involvement.
  • The study highlights the benefits of adaptable, in-house SOPs over rigid guidelines for complex autoimmune conditions.

Impact:

  • Highlights the need for standardized, interdisciplinary approaches in managing complex autoimmune diseases.
  • Demonstrates the practical advantages of in-house standardized operating procedures (SOPs) in clinical autoimmune disease management.
  • Calls for a national consensus to improve the structure, implementation, and integration of interdisciplinary autoimmune disease centers into routine care.