Monitoring momentary subjective well-being and psychotic experiences during antipsychotic dose reduction: Two single-case time series experience sampling method pilot study
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View abstract on PubMed
Summary
This summary is machine-generated.This study explored using a smartphone app for self-monitoring during antipsychotic dose reduction. The experience sampling method (ESM) app helped detect changes in well-being and psychotic symptoms in individuals with psychotic disorders.
Area Of Science
- Psychiatry and Mental Health
- Digital Health
- Personalized Medicine
Background
- Personalized dose optimization is crucial for improving well-being and rehabilitation in patients with psychotic disorders.
- N=1 trials are necessary to evaluate tools for self-managing functional outcomes during dose adjustments.
- Current methods may not adequately capture real-time changes in subjective experiences during medication reduction.
Purpose Of The Study
- To assess the feasibility of using an experience sampling method (ESM) smartphone app for monitoring subjective well-being and psychotic experiences.
- To determine if the ESM app can detect changes during and after antipsychotic dose reduction in two N=1 trials.
- To explore the potential of self-monitoring tools in optimizing medication dosage and supporting patient empowerment.
Main Methods
- Two participants with psychotic disorders in remission underwent gradual dose reduction.
- Subjective well-being (affective, physical) and momentary psychotic experiences were monitored using an ESM smartphone app.
- Time-series linear regression models analyzed changes during dose reduction phases compared to baseline.
Main Results
- One participant showed significant improvements in well-being and psychotic experiences during dose reduction.
- The second participant experienced worsened well-being and increased psychotic symptoms during the reduction phase.
- The ESM app successfully detected these divergent changes in subjective experiences.
Conclusions
- Self-monitoring with an ESM smartphone app can effectively detect changes in well-being and psychotic experiences during antipsychotic dose reduction.
- ESM tools may enhance patient control, empowerment, and facilitate shared decision-making in dose optimization.
- The findings highlight the need for individualized approaches due to high heterogeneity in psychotic disorders.
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