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Hyperglycemic Crises in Adults With Diabetes: A Consensus Report.
Guillermo E Umpierrez1, Georgia M Davis1, Nuha A ElSayed2,3
1Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
This updated consensus provides current guidance on managing diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) in adults. It offers evidence-based recommendations for diagnosis, treatment, and prevention for healthcare professionals and patients.
Area of Science:
- Endocrinology
- Metabolic Disorders
- Internal Medicine
Background:
- Previous ADA consensus statements on hyperglycemic crises were published in 2001 and updated in 2009.
- Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) remain significant complications in adults with diabetes.
Purpose of the Study:
- To update the consensus statement on hyperglycemic crises in adults with diabetes.
- To provide current knowledge on the epidemiology, pathophysiology, clinical presentation, diagnosis, treatment, and prevention of DKA and HHS.
- To inform healthcare professionals and individuals with diabetes.
Main Methods:
- A panel of internists and diabetologists convened to update the ADA consensus statement.
- Systematic examination of publications released since 2009 informed the new recommendations.
Main Results:
- The report synthesizes recent evidence to provide updated recommendations.
- New insights into DKA and HHS epidemiology, pathophysiology, and clinical presentation are included.
Conclusions:
- This consensus report offers the latest evidence-based guidelines for managing DKA and HHS in adults.
- The recommendations aim to improve the care and outcomes for individuals with diabetes experiencing hyperglycemic crises.
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