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Nomogram for fetal limb bones in Chinese ethnicity.
Ho Yin Diana Lee1, Wendy Shu1, Kwok Yiu Choi2
1Department of Obstetrics & Gynaecology, Pamela Youde Nethersole Eastern Hospital, Hong Kong.
Summary
This study created fetal limb bone nomograms for the Chinese population. Chinese fetal limb bones were found to be shorter than those in Caucasian and Afro-Caribbean populations.
Area of Science:
- Medical Imaging
- Fetal Development
- Anthropometry
Background:
- Accurate fetal biometry is crucial for assessing growth and development.
- Existing nomograms may not accurately reflect ethnic variations in fetal skeletal growth.
Purpose of the Study:
- To establish reference nomograms for fetal limb bone lengths in the Chinese ethnic population.
- To compare these measurements with existing nomograms from other ethnic groups.
Main Methods:
- Prospective cross-sectional study of 775 singleton pregnancies (12-37 weeks gestation).
- Standardized measurements of femur, tibia, fibula, humerus, ulna, radius, and foot length.
- Fractional polynomial regression used to generate 3rd, 10th, 50th, 90th, and 97th centiles.
Main Results:
- Established nomograms for Chinese fetal limb bones.
- Chinese fetal limb bone lengths were found to be shorter compared to Caucasian and Afro-Caribbean populations.
Conclusions:
- The developed nomograms are specific to the Chinese ethnic population.
- These ethnic-specific nomograms can help reduce misdiagnosis of short fetal limbs, decreasing associated anxiety and unnecessary interventions.
