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Updated: Jun 19, 2025

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
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Kidney Stone Risk in Normocalcemic Hyperparathyroidism before and after Parathyroid Surgery
Jie Tang1, Kamil Malshy2, Gyan Pareek2
1Division of Kidney Diseases and Hypertension Alpert Medical School of Brown University, Providence, RI, USA.
Abstract:
The higher risk for kidney stone in patients with primary hyperparathyroidism is well-documented; stone risk in patients with normocalcemic primary hyperparathyroidism (NPHPT) remains unclear. We present a case of recurrent calcium kidney stones in a patient with severe idiopathic hypercalciuria and NPHPT. The surgical resection of the parathyroid adenoma failed to reduce kidney stone risk (based on the 24-hr urine study) and kidney stone burden (based on ultrasound). This unique case examines the impact of surgical resection of an ectopic parathyroid adenoma on stone risk in a patient with NPHPT and recurrent calcium kidney stones.
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