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  11. Value Of Green Sign And Chicken Skin Aspects For Detecting Malignancy Of Colorectal Neoplasia In A Prospective Characterization Study

Value of green sign and chicken skin aspects for detecting malignancy of colorectal neoplasia in a prospective characterization study

Pierre Lafeuille1, Jérôme Rivory1, Alexandru Lupu1

  • 1Gastroenterology Department, Edouard Herriot Hospital, Lyon, France.

Endoscopy International Open
|July 26, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

The green sign is a valuable endoscopic feature for detecting malignant colorectal neoplasia, significantly improving the prediction of superficial and deep invasive lesions. This simple visual cue aids endoscopists in identifying cancerous growths more effectively.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Oncology

Background:

  • Accurate endoscopic characterization of colorectal lesions is crucial for predicting histology.
  • Distinguishing malignant from benign colorectal lesions endoscopically remains challenging for experts.
  • Simple endoscopic criteria can aid in the detection and prediction of malignancy.

Purpose of the Study:

  • To evaluate the diagnostic value of the "green sign" and "chicken skin" aspects in detecting malignant colorectal neoplasia.
  • To assess the accuracy of these endoscopic features for identifying superficial and deep invasive lesions.
  • To compare the efficacy of the green sign and chicken skin with existing classification systems.

Main Methods:

  • Prospective characterization and histological evaluation of consecutive colorectal lesions (Pro-CONECCT study).
Keywords:
Colorectal cancerDiagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE...)Endoscopy Lower GI TractPolyps / adenomas / ...

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  • Assessment of the diagnostic accuracy of the green sign and chicken skin for superficial and deep invasive lesions.
  • Statistical analysis including calculation of negative predictive values and adjusted odds ratios.

    • Main Results:

    • The study included 461 patients with 803 colorectal lesions.
    • The green sign demonstrated high negative predictive values for superficial (89.6%) and deep invasive lesions (98.1%).
    • The green sign provided additional diagnostic value for both lesion types compared to chicken skin and CONECCT classification (ORs 5.9 and 9.0, respectively).

    Conclusions:

    • The green sign is associated with malignant colorectal neoplasia.
    • Targeting areas with the green sign can improve the detection of focal malignancies.
    • This endoscopic feature aids in predicting the most severe histology of colorectal lesions.
    Tissue diagnosis