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Frailty and Cardiovascular Health

Kirstyn James1, Yasser Jamil2, Manish Kumar3

  • 1Department of Geriatric Medicine Cork University Hospital Cork Ireland.

Journal of the American Heart Association
|July 26, 2024
PubMed

Insights

Frailty and cardiovascular disease (CVD) worsen with age and are interconnected. Managing CVD risk factors may help frailty, impacting prevention and treatment strategies for older adults.

Area of Science:

  • Gerontology and Cardiovascular Medicine
  • Geriatric Syndromes and Cardiovascular Health

Background:

  • Aging populations experience increased incidence of frailty and cardiovascular disease (CVD).
  • Frailty and CVD share bidirectional relationships, common risk factors, and biological mechanisms.
  • Frailty is an independent prognostic marker in patients with CVD.

Purpose of the Study:

  • To review the current understanding of the frailty-CVD relationship.
  • To explore how CVD risk factor management influences frailty.
  • To examine frailty's impact on CVD management and clinical trial inclusion.

Main Methods:

  • Literature review of existing research on frailty and cardiovascular disease.
  • Analysis of the interplay between frailty, CVD risk factors, and management strategies.
  • Discussion of implications for clinical practice, research, and patient inclusion in trials.

Main Results:

  • Frailty significantly impacts primary and secondary CVD prevention strategies.
  • Frailty presents a barrier to enrolling CVD patients in clinical trials and advanced interventions.
  • Managing CVD risk factors shows potential for modifying frailty.

Conclusions:

  • Understanding the frailty-CVD link is crucial for optimizing geriatric cardiovascular care.
  • Future research should focus on effective frailty detection and modification in CVD patients.
  • Addressing frailty can improve outcomes and trial participation for individuals with cardiovascular disease.

Keywords:
agingcardiovascular diseasescardiovascular interventionsfrailtygeriatric syndromesprimary preventionsecondary prevention

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