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Related Experiment Videos

Anthralin therapy for alopecia areata.

D A Nelson, R L Spielvogel

    International Journal of Dermatology
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Low-dose topical anthralin did not benefit patients with alopecia areata (AA). A significant irritant contact dermatitis appears necessary for anthralin to be effective in treating AA.

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    Area of Science:

    • Dermatology
    • Immunology

    Background:

    • Topical anthralin is known to treat alopecia areata (AA).
    • This effect is associated with a strong irritant contact dermatitis.

    Purpose of the Study:

    • To investigate if low-dose topical anthralin, causing minimal skin irritation, benefits patients with AA.

    Main Methods:

    • A pilot clinical study was conducted.
    • Patients with AA received low-dose topical anthralin.

    Main Results:

    • No patients in the study experienced therapeutic benefits from the low-dose regimen.
    • Minimal contact dermatitis was observed.

    Conclusions:

    • Low-dose anthralin is ineffective for treating alopecia areata.
  • Effective therapy with anthralin for AA likely requires a significant irritant contact dermatitis.