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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Related Experiment Video

Updated: Jun 19, 2025

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COVID-19 and Prostatitis: A Review of Current Evidence.

Datesh Daneshwar1, Yemin Lee2, Abid Nordin3

  • 1Urology Clinic, Prince Court Medical Centre, 39, Jalan Kia Peng, Kuala Lumpur 50450, Malaysia.

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|July 26, 2024
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Summary

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may infect the prostate, potentially causing prostatitis. This review explores the association between COVID-19 and prostate health.

Keywords:
ACE2COVID-19SARS-CoV-2TMPRSS2prostatitis

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Area of Science:

  • Virology
  • Immunology
  • Urology

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global health concern.
  • SARS-CoV-2 utilizes ACE2 and TMPRSS2 to enter host cells, triggering a cytokine storm leading to organ damage.
  • Organs expressing both ACE2 and TMPRSS2 are susceptible to infection, potentially causing multiple-organ failure.

Purpose of the Study:

  • To investigate the potential association between SARS-CoV-2 infection and prostatitis.
  • To provide insights into the relationship between COVID-19 and prostate health.

Main Methods:

  • This is a review article.
  • Literature search on SARS-CoV-2, ACE2, TMPRSS2, and prostatitis.

Main Results:

  • The prostate gland expresses high levels of ACE2 and TMPRSS2 receptors.
  • Limited studies exist on COVID-19 and prostatitis, but the possibility of SARS-CoV-2-induced prostatitis cannot be excluded.

Conclusions:

  • The prostate's susceptibility to SARS-CoV-2 infection warrants further investigation.
  • Understanding this association is crucial for comprehensive patient care during the COVID-19 pandemic.