Current and Future Perspectives of Bioactive Glasses as Injectable Material

Andreea-Luiza Mîrț ^1,2,3,4, Denisa Ficai ^2,3,5,6, Ovidiu-Cristian Oprea ^2,3,5,6

⁰Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.

Nanomaterials (basel, Switzerland) +

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July 26, 2024

View abstract on PubMed

Summary

This review highlights recent bioactive glass composites, focusing on injectable formulations for biomedical applications. These advanced materials offer minimally invasive delivery, improving patient outcomes and treatment efficiency.

Area Of Science

Biomaterials Science
Materials Engineering
Medical Device Technology

Background

Bioactive glasses (BGs) are gaining attention for their regenerative potential in bone tissue engineering.
Recent research focuses on developing composite materials incorporating BGs for enhanced properties.
Injectable delivery systems are emerging as a minimally invasive alternative to traditional surgical methods.

Purpose Of The Study

To review recent advancements in bioactive glass composite formulations.
To emphasize inorganic and organic matrices used in injectable bioactive glass materials.
To highlight the clinical applications and advantages of these injectable bioactive glass composites.

Main Methods

Literature review of recent scientific publications on bioactive glasses and composites.
Analysis of inorganic and organic matrix materials used in injectable formulations.
Synthesis of information on clinical applications and performance of injectable bioactive glass systems.

Main Results

Bioactive glass composites are increasingly being developed, particularly for injectable applications.
Both inorganic and organic matrices are utilized to create injectable bioactive glass formulations.
These injectable materials demonstrate significant advantages, including minimally invasive delivery and uniform defect filling.

Conclusions

Injectable bioactive glass composites represent a significant advancement in biomedical applications.
Their minimally invasive nature offers benefits such as reduced patient discomfort and lower infection risk.
Further research into these materials promises improved clinical outcomes for various medical conditions.

Keywords:

bioactive glass biomaterials cements hydrogel

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