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UVEAL EFFUSION IN WALDENSTRÖM MACROGLOBULINEMIA: A CASE REPORT
Johanna Darmon1, Mickael Anjou1, Denis Georgelin2
1Department of Ophthalmology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France; and.
Purpose:
The objective of this study was to to report a case of Waldenström macroglobulinemia-related choroidal detachments.
Method:
This was a case report.
Results:
An 80-year-old woman was referred for bilateral visual loss for few months. She was hospitalized for Waldenström disease. Both anterior chambers were deep and quiet. The fundus revealed bilateral choroidal detachment without serous retinal detachments. No vitritis, retinal tear, or pigmented lesion was observed. After eliminating all other causes of uveal effusion, the patient was treated for her hemopathy with chemotherapy associated with corticosteroids and plasmapheresis. One month later, the fundus showed a complete disappearance of choroidal detachments and vision improved.
Conclusion:
Uveal effusion is an extremely rare ocular damage of Waldenström disease. Because choroidal vessels are porous, they may allow immunoglobulins, overproduced, to leak toward suprachoroidal space triggering choroidal detachments.
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