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  1. Home
  3. The Contribution Of Intimate Partner Violence To Vertical Hiv Transmission: A Modelling Analysis Of 46 African Countries.
  1. Home
  3. The Contribution Of Intimate Partner Violence To Vertical Hiv Transmission: A Modelling Analysis Of 46 African Countries.

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The contribution of intimate partner violence to vertical HIV transmission: a modelling analysis of 46 African

Salome Kuchukhidze1, Magdalene K Walters2, Dimitra Panagiotoglou1

  • 1Department of Epidemiology and Biostatistics, School of Population and Global Health, McGill University, Montréal, QC, Canada.

The Lancet. HIV
|July 26, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Intimate partner violence (IPV) contributes to 13% of paediatric HIV infections in sub-Saharan Africa. Addressing IPV is crucial for eliminating vertical HIV transmission, particularly among young women.

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Area of Science:

  • Public Health
  • Epidemiology
  • Gender Studies

Background:

  • Gender inequities and intimate partner violence (IPV) increase HIV vulnerability and hinder care access.
  • Sub-Saharan Africa bears a high burden of IPV and accounts for most pediatric HIV infections.
  • Understanding the link between IPV and vertical HIV transmission is critical for elimination strategies.

Purpose of the Study:

  • To quantify the proportion of vertical HIV transmission attributable to IPV in sub-Saharan Africa.
  • To estimate the excess risk of vertical HIV transmission associated with IPV.

Main Methods:

  • A probability tree model was used to analyze vertical HIV transmission in 46 African countries.
  • Data from UNAIDS, WHO, and literature were incorporated, considering factors like fertility, HIV prevalence, and ART retention.
  • Population attributable fraction (PAF) and excess transmission risk per 1000 births were calculated, with uncertainty intervals determined via Monte Carlo simulations.

    • Main Results:

    • IPV accounted for 13% (over 22,000 infections) of pediatric HIV infections in 2022 across 46 countries.
    • The population attributable fraction (PAF) for IPV ranged from 4% in Niger to 28% in Uganda.
    • Young women aged 15-19 years showed the highest PAF (20%), while southern Africa reported 11 additional infections per 1000 births among women affected by IPV.

    Conclusions:

    • IPV is linked to approximately one in eight pediatric HIV infections in sub-Saharan Africa.
    • Eliminating IPV could significantly accelerate the end of vertical HIV transmission, especially for young women.
    • Targeted interventions addressing IPV are essential for HIV prevention and elimination efforts.