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Mucosal Site Detection of Herpes Simplex Virus in Neonates

Rachel J Graf1, Ingrith Viviana Hoyos García2, Alvaro Dendi3

  • 1The Ohio State University College of Medicine, Columbus, OH; Division of Neonatology, Department of Pediatrics, Nationwide Children's Hospital, Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Perinatal Research, Ohio Perinatal Research Network, Columbus, OH.

The Journal of Pediatrics
|July 26, 2024
PubMed
Abstract

Keywords:
PCRacyclovirneonatal herpesneonate

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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