Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Hemodynamic effects of synchronous and asynchronous independent lung ventilation with different levels of positive end-expiratory pressure and tidal volumes on unilateral lung injury in dogs].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2010
Same author

[Study on the immuno-effects and influencing factors of Chinese hamster ovary (CHO) cell hepatitis B vaccine among adults, under different dosages].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2010
Same author

Assemblies of fluorine containing bent-shaped liquid crystal molecules studied by using scanning tunneling microscopy.

Journal of nanoscience and nanotechnology·2010
Same author

Carbon nanotubes induce secondary structure changes of bovine albumin in aqueous phase.

Journal of nanoscience and nanotechnology·2010
Same author

[Immunogenicity and protective efficacy of pertactin recombinants against Bordetella bronchiseptica challenge].

Wei sheng wu xue bao = Acta microbiologica Sinica·2010
Same author

[Analysis of the electrocardiographic findings in 288 patients with acute pulmonary thromboembolism].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2010
Same journal

Kinematic tracking of the small bones of the wrist in sequential 3DCT and dynamic 4DCT volume images using open-source Hierarchical 3D Registration, a module within SlicerAutoscoper<sup>M</sup>.

Biomedical engineering online·2026
Same journal

Technical and clinical feasibility of single-use gastroscopy with real-time AI-based quality monitoring and single-use colonoscopy: a prospective two-center study.

Biomedical engineering online·2026
Same journal

Non-invasive classification of stable HFpEF using a deep learning model trained on acoustic features of sustained vowels.

Biomedical engineering online·2026
Same journal

Lung cancer multimodal auxiliary diagnosis based on entropy weight decision fusion.

Biomedical engineering online·2026
Same journal

Potentials of BMSCs for regulating osteogenic-vascular-neural-lymphatic coupling in bone regeneration.

Biomedical engineering online·2026
Same journal

Protein adsorption at material interface: mechanistic design framework for engineering ceramic scaffolds for bone repair applications.

Biomedical engineering online·2026
See all related articles

Related Experiment Video

Updated: Jun 19, 2025

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

14.3K

A glaucoma micro-stent with diverging channel and stepped shaft structure based on microfluidic template processing

Chen Wang1, Fule Wang1, Yunru Liao2,3

  • 1School of Mechanical and Power Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.

Biomedical Engineering Online
|July 26, 2024
PubMed
Summary
This summary is machine-generated.

A novel diverging drainage stent for glaucoma surgery shows improved mechanical properties and higher drainage efficiency compared to existing options. This innovation offers a promising, cost-effective solution for minimally invasive glaucoma surgery (MIGS).

Keywords:
Drainage efficiencyDrainage stentGlaucomaMIGSMicrofluidic channel processingPDMS

More Related Videos

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
10:26

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

Published on: August 17, 2017

13.1K
Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.1K

Related Experiment Videos

Last Updated: Jun 19, 2025

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

14.3K
Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
10:26

Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

Published on: August 17, 2017

13.1K
Interlinked Macroporous 3D Scaffolds from Microgel Rods
07:32

Interlinked Macroporous 3D Scaffolds from Microgel Rods

Published on: June 16, 2022

2.1K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Materials Science

Background:

  • Minimally invasive glaucoma surgery (MIGS) is increasingly popular, with micro-stents forming its core.
  • Current micro-stents face limitations due to short-term and long-term complications.
  • A novel drainage stent with a diverging channel is proposed to address these issues.

Purpose of the Study:

  • To develop a novel drainage stent implant with a diverging channel using microfluidic template processing.
  • To evaluate the mechanical properties, biocompatibility, and implantation feasibility of the new stent.
  • To compare the novel stent's performance against commercial XEN gel stents.

Main Methods:

  • Microfluidic template processing technology was employed to fabricate the diverging channel stent.
  • Mechanical properties, including stress concentration and bending resistance, were theoretically analyzed.
  • Drainage efficiency was calculated and compared to commercial stents.
  • In vivo and in vitro experiments were conducted to assess biocompatibility and material stability.

Main Results:

  • The novel stent exhibited a stress concentration value 2-3 times lower than XEN stents, suggesting superior bending resistance.
  • Theoretical drainage efficiency was approximately 5.76 times higher for the diverging stent compared to XEN stents.
  • In vivo studies at three months showed no cytotoxicity, indicating favorable biocompatibility.
  • The stent demonstrated excellent material stability in in vitro simulations.

Conclusions:

  • The diverging drainage stent offers a novel, cost-effective, and efficient method for preparing MIGS devices.
  • This new stent provides an additional option for filtering treatment in glaucoma management.
  • The findings support the potential of this novel stent for improving glaucoma surgical outcomes.