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Influenza in Pregnancy: Maternal, Obstetric, and Fetal Implications, Diagnosis, and Management

Sarah K Dotters-Katz1

  • 1Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina.

Clinical Obstetrics and Gynecology
|July 27, 2024
PubMed

Influenza(flu) in pregnancy is associated with higher rates of hospitalization, ICU admission, and death and with increased odds of congenital anomalies and stillbirth, but not preterm birth. Clinical manifestations of flu in pregnancy are the same as nonpregnant patients. Pregnant individuals with flu-like symptoms or flu exposure should be treated with antivirals. Diagnostic testing is not needed. Oseltamivir is the mainstay of treatment(and prophylaxis), and when given within 48 hours of symptom onset, it decreases morbidity and mortality. Influenza is associated with worse maternal, obstetric, and neonatal outcomes. These risks are mitigated by early oseltamivir treatment and maternal vaccination; hence the recommendation for universal vaccination in pregnancy.

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