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Updated: Jun 19, 2025

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Published on: October 2, 2019
The Complex Relationship between Sleep and Cognitive Reserve: A Narrative Review Based on Human Studies
Francesca Balsamo1,2, Erica Berretta2, Debora Meneo1
1Department of Human Sciences, Guglielmo Marconi University, 00193 Rome, Italy.
Good sleep builds cognitive reserve, which in turn helps protect brain function against sleep disturbances and aging. Understanding this connection is key for brain health.
Area of Science:
- Neuroscience
- Cognitive Science
- Sleep Research
Background:
- Sleep and cognitive reserve are vital for lifelong well-being and cognitive function.
- The interplay between sleep and cognitive/neural reserve requires further investigation.
Purpose of the Study:
- To explore the bidirectional relationship between sleep and cognitive/neural reserve.
- To understand how sleep and reserve influence human cognitive functions.
Main Methods:
- Systematic literature search of PubMed up to February 6, 2024.
- Inclusion criteria applied to select 11 relevant articles for review.
- Analysis focused on the connection between sleep and cognitive/neural reserve.
Main Results:
- Sleep acts as a crucial factor in building cognitive reserve.
- Cognitive reserve moderates the impact of sleep (healthy or disturbed) on cognitive functions.
- A strong link exists between sleep, cognitive reserve, and overall cognitive performance.
Conclusions:
- Both sleep and cognitive reserve are essential for maintaining cognitive function.
- Further research into their interaction is needed to develop strategies for brain health.
- Enhanced understanding can improve resilience against age-related cognitive decline and pathologies.
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