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Published on: November 28, 2016
Emerging Microorganisms and Infectious Diseases: One Health Approach for Health Shared Vision.
Maria Vittoria Ristori1, Valerio Guarrasi2, Paolo Soda2,3
1Operative Research Unit of Laboratory, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128 Rome, Italy.
Emerging infectious diseases (EIDs) require advanced approaches. Integrating omics data and bioinformatics tools aids in rapid pathogen identification and effective management of EIDs.
Area of Science:
- Infectious Diseases
- Bioinformatics
- Public Health
Background:
- Emerging infectious diseases (EIDs) pose a significant global health threat.
- Factors include microbial adaptation and host/environmental characteristics.
- Examples include SARS, MERS, COVID-19, influenza, and West Nile fever.
Purpose of the Study:
- To explore novel strategies for identifying and managing emerging infectious diseases.
- To highlight the role of the One Health approach and omics integration.
- To discuss the application of bioinformatics and machine learning in infectious disease control.
Main Methods:
- Utilizing the One Health approach for pathogen identification.
- Integrating omics data (genomics, proteomics, etc.) for microbial analysis.
- Employing bioinformatics and machine learning for data analysis and prediction.
Main Results:
- Omics integration and bioinformatics enable rapid identification of high-priority microorganisms.
- Machine learning aids in early diagnosis, treatment prediction, and antibiotic selection.
- Data integration tools facilitate clinical management of EIDs.
Conclusions:
- Advanced bioinformatics and omics technologies are crucial for detecting and preventing epidemics.
- The One Health approach combined with computational tools enhances surveillance and response.
- Innovative data integration strategies improve the clinical management of emerging infectious diseases.
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