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Updated: Jun 19, 2025

mirMachine: A One-Stop Shop for Plant miRNA Annotation
Published on: May 1, 2021
MicroRNA166: Old Players and New Insights into Crop Agronomic Traits Improvement
Zhanhui Zhang1, Tianxiao Yang2, Na Li1
1National Key Laboratory of Wheat and Maize Crop Science/Collaborative Innovation Center of Henan Grain Crops/College of Agronomy, Henan Agricultural University, Zhengzhou 450002, China.
Abstract:
MicroRNA (miRNA), a type of non-coding RNA, is crucial for controlling gene expression. Among the various miRNA families, miR166 stands out as a highly conserved group found in both model and crop plants. It plays a key role in regulating a wide range of developmental and environmental responses. In this review, we explore the diverse sequences of MIR166s in major crops and discuss the important regulatory functions of miR166 in plant growth and stress responses. Additionally, we summarize how miR166 interacts with other miRNAs and highlight the potential for enhancing agronomic traits by manipulating the expression of miR166 and its targeted HD-ZIP III genes.
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