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Published on: November 9, 2019
Cobalt-Catalyzed Reduction of Aldehydes to Alcohols via the Hydroboration Reaction
Dariusz Lewandowski1, Grzegorz Hreczycho1
1Faculty of Chemistry, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego St. 8, 61-614 Poznan, Poland.
Abstract:
A method for the reduction of aldehydes with pinacolborane catalyzed by pincer cobalt complexes based on a triazine backbone is developed in this paper. The presented methodology allows for the transformation of several aldehydes bearing a wide range of electron-withdrawing and electron-donating groups under mild conditions. The presented procedure allows for the direct one-step hydrolysis of the obtained intermediates to the corresponding primary alcohols. A plausible reaction mechanism is proposed.
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