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Energetics of myocardial function.

P A Molé, R L Coulson

    Medicine and Science in Sports and Exercise
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Prolonged exercise, especially in heat, causes cardiovascular drift, reducing stroke volume. However, the heart

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    Area of Science:

    • Exercise Physiology
    • Cardiovascular Physiology

    Background:

    • Understanding the heart's response to prolonged exercise is crucial for athletes and health.
    • Cardiovascular drift is a known phenomenon during sustained physical exertion.

    Purpose of the Study:

    • To review the available literature on cardiac resistance to deterioration during prolonged exercise.
    • To analyze the physiological mechanisms underlying cardiovascular responses to exhaustive exercise.

    Main Methods:

    • Literature review of studies on prolonged exercise and cardiovascular function.
    • Analysis of physiological data including oxygen consumption (VO2), cardiac output, stroke volume, and heart rate.

    Main Results:

    • Whole body VO2 increases with vigorous exercise, mainly in working muscles.

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  • Heat exacerbates VO2 rise and contributes to cardiovascular drift (decreased mean arterial pressure and stroke volume, increased heart rate).
  • Reduced ventricular filling pressure, due to decreased central venous volume, contributes to lower stroke volume.

    • Conclusions:

    • The heart exhibits some resilience, as myocardial energetics and estimated work do not significantly change after 1 hour of exercise in temperate conditions.
    • However, prolonged exercise in heat leads to cardiovascular drift, impacting cardiac function through reduced stroke volume.
    • Further research is needed to fully understand potential decreases in the heart's inotropic state during exhaustive exercise.