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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

177
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
177

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Related Experiment Video

Updated: Jun 18, 2025

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

241

Risk Factors for Rectal Cancer Recurrence after Local Excision of T1 Lesions from a Decade-Long Multicenter

Yaron Rudnicki1, Nitzan Goldberg1, Nir Horesh2

  • 1Department of Surgery, Meir Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.

Journal of Clinical Medicine
|July 27, 2024
PubMed
Summary

Local surgical excision for early rectal cancer is safe, but recurrence is possible. Larger tumors, mucinous histology, and involved margins increase recurrence risk, suggesting closer surveillance for high-risk patients.

Keywords:
early rectal cancerlocal excisionrectal cancer recurrencet1 rectal cancer

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Rectal Cancer Research

Background:

  • Local surgical excision is a standard treatment for T1 rectal adenocarcinoma.
  • Key questions remain regarding recurrence rates and associated risk factors following this procedure.

Purpose of the Study:

  • To identify risk factors for local and systemic recurrence after local excision of T1 rectal adenocarcinoma.
  • To evaluate the safety and efficacy of local excision for early rectal cancer.

Main Methods:

  • Retrospective multicenter study of 97 patients with T1 rectal lesions undergoing local excision (2010-2020).
  • Data analysis included demographics, surgical details, outcomes, and recurrence patterns.
  • Univariable and multivariable logistic regression identified risk factors for recurrence.

Main Results:

  • The overall recurrence rate was 14.4%, with local recurrence in 11 patients and systemic recurrence in 6.
  • Significant risk factors for recurrence included larger tumor size (OR 6.67), mucinous histology (OR 14.02), and involved margins (OR 9.59).
  • 24.7% of patients required additional treatment post-pathology.

Conclusions:

  • Local excision is a safe and viable option for T1 rectal cancer.
  • High-risk features (large tumors, mucinous histology, involved margins) are associated with increased recurrence.
  • Stricter surveillance and potential additional interventions are recommended for high-risk patients.