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Related Concept Videos

Measurement of Fluid Pressure01:16

Measurement of Fluid Pressure

Fluid pressure is commonly measured using devices called manometers, which rely on liquid columns to indicate pressure differences. The height of a liquid column in a manometer reflects the pressure exerted by the fluid, providing a simple yet effective means of measurement. Different types of manometers serve specific purposes based on their configurations and the type of fluids involved.
A basic form of manometer is the piezometer, a vertical tube open at the top and filled with the same...

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Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
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Wireless and Battery-Free Sensor for Interstitial Fluid Pressure Monitoring.

Chengyang Qian1, Fan Ye2, Junye Li1

  • 1Department of Biomedical Engineering, Henry Samueli School of Engineering, University of California Irvine, Irvine, CA 92697, USA.

Sensors (Basel, Switzerland)
|July 27, 2024
PubMed
Summary
This summary is machine-generated.

A new wireless sensor monitors interstitial fluid pressure (IFP) to predict congestive heart failure (CHF) exacerbations. This implantable device offers continuous monitoring for early intervention, potentially reducing hospital readmissions.

Keywords:
LC inductive couplingheart failure biomarker detectionwireless pressure sensor

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Area of Science:

  • Biomedical Engineering
  • Medical Devices
  • Cardiology

Background:

  • Congestive heart failure (CHF) is a progressive, incurable disease leading to fluid accumulation and frequent hospitalizations.
  • Continuous monitoring of CHF patients is crucial for early intervention and slowing disease progression.
  • Interstitial fluid pressure (IFP) increases during CHF exacerbation, serving as a potential predictive biomarker.

Purpose of the Study:

  • To develop a novel subcutaneous wireless sensor for continuous interstitial fluid pressure (IFP) monitoring.
  • To enable early detection of congestive heart failure (CHF) exacerbations.
  • To provide a low-cost, implantable solution for long-term patient management.

Main Methods:

  • Design and fabrication of an inductor-capacitor (LC) sensor using inexpensive planar copper coils.
  • Utilizing silicone rubber as a dielectric material for the sensor.
  • Testing the sensor's wireless communication capabilities through 12.7 mm of tissue and measuring its sensitivity.

Main Results:

  • The developed LC sensor is battery-free and capable of wireless data transmission.
  • The sensor can communicate through 12.7 mm of tissue (4 skin layers).
  • In vitro simulations showed an average sensitivity of -8.03 MHz/mmHg.

Conclusions:

  • The developed LC sensor is a promising tool for subcutaneous wireless and continuous IFP monitoring.
  • This technology can aid in the early prediction and management of congestive heart failure (CHF) exacerbations.
  • The sensor's low-profile, inexpensive design facilitates potential clinical translation for improved patient outcomes.