Related Experiment Video
Updated: May 10, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids
Andrew Noel1, Jianqiang Zhang1, Huigang Shen1
1Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Abstract:
A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia. Hypothesis-free metagenomics identified a previously unreported picornavirus (USA/IA26017/2023), and further phylogenetic analysis classified USA/IA26017/2023 as an aphthovirus related to bovine rhinitis B virus. Viral nucleic acid was localized to lesions of bronchitis using in situ hybridization. This marks the first report of a picornavirus putatively causing respiratory disease in goats and highlights the potential for cross-species transmission of aphthoviruses.
More Related Videos
Related Concept Videos
Pneumonia II: Pathophysiology
Microbiota of the Respiratory Tract
Atypical Pneumonia
Bacterial Meningitis II: Pathophysiology
Asthma I: Introduction
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

