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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Delphi method applicability in drug foresight
Tomi Lintonen1, Karoliina Karjalainen2, Sanna Rönkä2
1Finnish Foundation for Alcohol Studies, PO Box 30, Helsinki, FI-00271, Finland. tomi.lintonen@alkoholitutkimussaatio.fi.
Expert predictions on drug use trends in Finland were largely accurate for up to ten years, correctly forecasting increased drug use and acceptance. However, predicting shifts in specific drug popularity, like new psychoactive substances, proved more challenging.
Area of Science:
- Drug policy and public health research.
- Foresight studies and trend analysis in substance use.
Background:
- Expert predictions on drug-related topics in Finland were made between 2009-2011.
- The study assesses the accuracy of these foresight predictions for the year 2020.
Purpose of the Study:
- To evaluate the accuracy of expert foresight predictions regarding drug use and drug policy in Finland.
- To determine the reliability of long-term (10-year) drug-related trend forecasting.
Main Methods:
- Utilized multiple data sources including statistics, surveys, official registers, and wastewater analyses.
- Compared expert predictions from a 2009-2011 Delphi study with 2020 data.
Main Results:
- Experts accurately predicted increased drug use and wider societal approval, though the latter was slow.
- The rise in buprenorphine misuse was noted, while new synthetic drug use did not markedly increase.
- Drug prices remained stable; legislation saw no changes, but enforcement became more lenient, aligning with expert foresight.
Conclusions:
- Forecasting existing trends (e.g., increased drug use) is more reliable than predicting shifts in specific drug popularity (e.g., NPS).
- Foresight studies can provide accurate views of drug-related issues up to a decade in advance.
- Expert disagreement highlights future uncertainties; organized crime's role in drug trade was predicted but not preventable.
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