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Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Related Experiment Video

Updated: Jun 18, 2025

Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
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Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension

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Right ventricular dysfunction: pathophysiology, experimental models, evaluation, and treatment.

Carlos Real1, Carlos Nicolás Pérez-García2, Carlos Galán-Arriola2

  • 1Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; Servicio de Cardiología, Hospital Universitario Clínico San Carlos, Madrid, Spain.

Revista Espanola De Cardiologia (English Ed.)
|July 28, 2024
PubMed
Summary

Understanding right ventricular (RV) function is crucial for many diseases. This review updates knowledge on RV physiology, dysfunction, and treatment, highlighting current challenges and future directions in RV research.

Keywords:
Disfunción ventricular derechaExperimental modelsModelos experimentalesRight ventricleRight ventricular dysfunctionVentrículo derecho

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Area of Science:

  • Cardiology
  • Physiology
  • Pathology

Background:

  • Growing interest in the right ventricle's role in various diseases.
  • Significant gaps remain in understanding RV dysfunction mechanisms.
  • Current diagnostic and treatment strategies for RV issues are limited.

Purpose of the Study:

  • To provide an updated overview of right ventricular physiology.
  • To explore the transition from normal function to dysfunction.
  • To review current diagnostic tools and therapeutic options for the right ventricle.

Main Methods:

  • Literature review of recent advances in right ventricular research.
  • Synthesis of information on RV pathophysiology and clinical implications.
  • Focus on a translational perspective, linking basic science to clinical practice.

Main Results:

  • The right ventricle's complex physiology is increasingly recognized.
  • Right ventricular dysfunction is a significant prognostic factor in many conditions.
  • Effective diagnostic and therapeutic strategies are still evolving.

Conclusions:

  • Further research is needed to fully elucidate RV dysfunction mechanisms.
  • Improved diagnostic tools are essential for timely intervention.
  • Development of targeted therapies for right ventricular diseases is a priority.