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Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study
Tianna Zhou1, Mitsuaki Sawano2, Adith S Arun1
1Yale School of Medicine, New Haven, Conn.
The American Journal of Medicine
|July 28, 2024
Summary
Long COVID patients with internal tremors and vibrations report worse health and more new-onset conditions like mast cell and neurologic disorders. These symptoms distinguish a subset of long COVID patients with unique health challenges.
Area of Science:
- Neurology
- Immunology
- Public Health
Background:
- Internal tremors and vibrations, known neurological symptoms, are increasingly recognized in long COVID.
- Limited research has detailed the specific comorbidities and new-onset conditions associated with these symptoms in long COVID patients.
Purpose of the Study:
- To compare pre-pandemic comorbidities, new-onset conditions, and long COVID symptoms in individuals experiencing internal tremors/vibrations versus those without these symptoms.
Main Methods:
- The Yale Listen to Immune, Symptom and Treatment Experiences Now (LISTEN) Study surveyed 423 adults with long COVID.
- Internal tremors/vibrations were the exposure variable, with demographic, comorbidity, and symptom data as outcomes.
Main Results:
- 37% of long COVID patients reported internal tremors/vibrations.
- These patients, while similar in pre-pandemic comorbidities, reported worse health status (Euro-QoL visual analogue scale) and higher rates of new-onset mast cell disorders and neurologic conditions.
Conclusions:
- Internal tremors and vibrations in long COVID are associated with distinct co-occurring conditions and a poorer health status.
- Identifying these symptom clusters can aid in understanding and managing diverse long COVID presentations.
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