Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

Breathing

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Inhaled Medications

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Respiratory Outcomes in Children With Neonatal Respiratory Distress Syndrome and Monoallelic ABCA3 Variants.

Pediatric pulmonology·2026

Same author

Place-Based Inequities in E-Cigarette/Vape and Cannabis Retail Density in Massachusetts: The Role of Child Opportunity and Social Vulnerability.

Chest·2026

Same author

Late-Presenting Congenital Diaphragmatic Hernia Initially Diagnosed as a Splenule on CT Imaging.

Pediatrics·2026

Same author

Declining use of discussion boards in AI era.

Medical education·2025

Same author

Association between Subspecialty In-Training Examination Scores and First Attempt Results in Neonatal-Perinatal Medicine Boards.

American journal of perinatology·2025

Same author

Treatment of Nicotine Use in Adolescents Under 18 Years of Age: An Official American Thoracic Society Clinical Practice Guideline.

American journal of respiratory and critical care medicine·2025

Search research articles

Related Experiment Video

Updated: Jun 18, 2025

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

Published on: August 4, 2021

Innovations in Childhood Interstitial and Diffuse Lung Disease.

Alicia Casey¹, Elizabeth K Fiorino², Jennifer Wambach³

¹Department of Pediatrics, Division of Pulmonary Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA 02115, USA.

Clinics in Chest Medicine

|July 28, 2024

Summary

This summary is machine-generated.

Children's interstitial and diffuse lung diseases (chILDs) are diverse lung disorders in children. Innovations in diagnosis and care, including multidisciplinary teams and research networks, are improving outcomes for these complex conditions.

Keywords:

Childhood interstitial lung disease Neuroendocrine hyperplasia of infancy Pediatric pulmonology Pulmonary fibrosis Surfactant dysfunction

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Direct Tracheal Instillation of Solutes into Mouse Lung

Direct Tracheal Instillation of Solutes into Mouse Lung

Published on: August 29, 2010

Related Experiment Videos

Last Updated: Jun 18, 2025

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

Published on: August 4, 2021

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Direct Tracheal Instillation of Solutes into Mouse Lung

Direct Tracheal Instillation of Solutes into Mouse Lung

Published on: August 29, 2010

Area of Science:

Pediatric Pulmonology
Rare Diseases
Medical Diagnostics

Background:

Children's interstitial and diffuse lung diseases (chILDs) represent a heterogeneous group of rare pulmonary conditions affecting infants and children.
These disorders manifest with respiratory symptoms and diffuse lung abnormalities on imaging, leading to substantial healthcare utilization, morbidity, and mortality.

Purpose of the Study:

To review past and current innovations in the diagnosis and clinical management of chILDs.
To highlight advancements in multidisciplinary care and collaborative research efforts.

Main Methods:

Literature review of diagnostic and clinical care innovations for chILDs.
Analysis of the impact of multidisciplinary care and patient research networks.

Main Results:

Significant improvements in chILD patient care have been achieved through collaborative efforts.
Multidisciplinary care models and established research networks have enhanced diagnosis and management strategies.

Conclusions:

Multicenter collaboration and patient research networks are crucial for advancing the care of children with chILDs.
Ongoing innovations in diagnosis and clinical practice are vital for improving outcomes in these complex pediatric lung diseases.