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Published on: August 4, 2021
Innovations in Childhood Interstitial and Diffuse Lung Disease
Alicia Casey1, Elizabeth K Fiorino2, Jennifer Wambach3
1Department of Pediatrics, Division of Pulmonary Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA 02115, USA.
Insights
Children's interstitial and diffuse lung diseases (chILDs) are diverse lung disorders in children. Innovations in diagnosis and care, including multidisciplinary teams and research networks, are improving outcomes for these complex conditions.
Area of Science:
- Pediatric Pulmonology
- Rare Diseases
- Medical Diagnostics
Background:
- Children's interstitial and diffuse lung diseases (chILDs) represent a heterogeneous group of rare pulmonary conditions affecting infants and children.
- These disorders manifest with respiratory symptoms and diffuse lung abnormalities on imaging, leading to substantial healthcare utilization, morbidity, and mortality.
Purpose of the Study:
- To review past and current innovations in the diagnosis and clinical management of chILDs.
- To highlight advancements in multidisciplinary care and collaborative research efforts.
Main Methods:
- Literature review of diagnostic and clinical care innovations for chILDs.
- Analysis of the impact of multidisciplinary care and patient research networks.
Main Results:
- Significant improvements in chILD patient care have been achieved through collaborative efforts.
- Multidisciplinary care models and established research networks have enhanced diagnosis and management strategies.
Conclusions:
- Multicenter collaboration and patient research networks are crucial for advancing the care of children with chILDs.
- Ongoing innovations in diagnosis and clinical practice are vital for improving outcomes in these complex pediatric lung diseases.
Abstract:
Children's interstitial and diffuse lung diseases (chILDs) are a heterogenous and diverse group of lung disorders presenting during childhood. Infants and children with chILD disorders present with respiratory signs and symptoms as well as diffuse lung imaging abnormalities. ChILD disorders are associated with significant health care resource utilization and high morbidity and mortality. The care of patients with chILD has been improved through multidisciplinary care, multicenter collaboration, and the establishment of patient research networks in the United Stated and abroad. This review details past and current innovations in the diagnosis and clinical care of children with chILD.
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