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Race, Ethnicity, and Pediatric Postsurgical Mortality: Current Trends and Future Projections
Olubukola O Nafiu1, Christian Mpody1, Titilopemi A Aina2
1Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Insights
Racial disparities in pediatric surgery lead to thousands of excess deaths annually. Addressing these inequalities could prevent over 1100 Black children's deaths in the next decade.
Area of Science:
- Pediatric surgery outcomes
- Health equity research
- Public health policy
Background:
- Aggregate human costs of pediatric postsurgical mortality disparities remain unquantified in the US.
- Understanding racial inequalities in pediatric surgical outcomes is crucial for clinicians, policymakers, and the public.
Purpose of the Study:
- To contextualize the human costs of racial disparities in pediatric postsurgical mortality.
- To estimate excess deaths among Black and Hispanic children compared to white children.
- To evaluate policy interventions for reducing pediatric surgical mortality disparities.
Main Methods:
- Population-based study of 673,677 children undergoing intermediate to high-risk surgery (2000-2019).
- Estimation of excess deaths attributable to racial disparities.
- Modeling of mortality reduction targets and impact of a 2.5% annual reduction policy.
Main Results:
- Consistently higher risk-adjusted postoperative mortality for Black (aRR: 1.42) and Hispanic (aRR: 1.22) children versus white children.
- Disparities were more pronounced in nonteaching hospitals.
- 10,200 excess deaths occurred among minoritized children (average 536/year); a 2.5% annual reduction could prevent ~1100 Black children's deaths in a decade.
Conclusions:
- The study quantifies excess pediatric postsurgical deaths due to racial disparities.
- A framework is proposed to reduce pediatric postoperative mortality disparities within ten years.
- Focusing on solutions can guide actionable policy changes for improved child surgical outcomes.
Background:
No study has contextualized the aggregate human costs attributable to disparities in pediatric postsurgical mortalities in the United States, a critical step needed to convey the scale of racial inequalities to clinicians, policymakers, and the public.
Methods:
We conducted a population-based study of 673 677 children from US hospitals undergoing intermediate to high-risk surgery between 2000 and 2019. We estimated the excess deaths that could be avoided if Black and Hispanic children had comparable mortality rates to white children. We estimated the mortality reduction required to eliminate disparities within the next decade. We finally evaluated the impact of policy changes targeting a modest annual 2.5% reduction in disparity-attributable mortality.
Results:
During 2000 to 2019, risk-adjusted postoperative mortality trended consistently higher for both Black (adjusted RR [aRR]: 1.42, 95% confidence interval [CI]: 1.36-1.49) and Hispanic children (aRR: 1.22, 95% CI: 1.17-1.27) than for white children. These disparity gaps were driven by higher mortality in Black and Hispanic children receiving surgery in nonteaching hospitals (Black versus white aRR: 1.63, 95% CI: 1.38-1.93; Hispanic versus white aRR: 1.50, 95% CI: 1.33-1.70). There were 4700 excess deaths among Black children and 5500 among Hispanic children, representing. 10 200 (average: 536 per year) excess deaths among minoritized children. Policy changes achieving an annual 2.5% reduction in postoperative mortality would prevent approximately 1100 deaths among Black children in the next decade.
Conclusions:
By exploring the solution, and not just the problem, our study provides a framework to reduce disparities in pediatric postoperative mortality over the next decade.
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