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Brunner's gland adenomas in two cats
Elizabeth S Hines1, Paula Roberta Giaretta2, João Pedro Cavasin2
1Department of Veterinary Pathobiology, Texas A&M University, School of Veterinary Medicine & Biomedical Sciences, College Station, TX, USA.
JFMS Open Reports
|July 29, 2024
Summary
This study describes the first documented cases of Brunner's gland (BG) adenomas in cats, rare duodenal tumors. One cat had an unknown polyp significance, while the other experienced vomiting relief after surgery for a non-resectable mass.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
Background:
- Brunner's gland (BG) adenomas are rare, typically benign tumors in humans.
- These lesions and BG hyperplasia have been infrequently documented in animals, including dogs, horses, rodents.
- This study marks the first report of BG adenomas in feline patients.
Observation:
- Two cats, aged 13.5 and 14 years, presented with duodenal masses.
- Histological examination revealed well-differentiated Brunner's gland adenomas in both cases.
- One cat had a proximal duodenal polyp near the major duodenal papilla; the other had a mural mass causing vomiting.
Findings:
- The first cat's duodenal polyp significance remains unknown due to euthanasia for unrelated reasons.
- The second cat's non-resectable duodenal mass resolved vomiting after palliative gastroenterostomy surgery.
- The second cat survived 35 months post-procedure, indicating potential for long-term management.
Implications:
- This research establishes the occurrence of Brunner's gland adenomas in cats.
- It provides a basis for comparative pathology and differential diagnosis of feline duodenal masses.
- Understanding these feline BG adenomas may inform future diagnostic and therapeutic strategies in veterinary medicine.

