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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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Overactive Bladder (OAB) Symptoms in Patients Undergoing Flexible Cystoscopy
Rafiullah Khan1, Syed M Nazim1, Shahid Iqbal2
1Surgery, Aga Khan University Hospital, Karachi, PAK.
Cureus
|July 29, 2024
Summary
Flexible cystoscopy can temporarily worsen overactive bladder (OAB) symptoms, sometimes causing new-onset OAB. These symptoms usually resolve on their own within days, aiding patient counseling and future management strategies.
Area of Science:
- Urology
- Patient Outcomes
Background:
- Overactive bladder (OAB) symptoms can significantly impact quality of life.
- Flexible cystoscopy is a common urological procedure.
Purpose of the Study:
- To measure changes in OAB symptoms post-flexible cystoscopy.
- To evaluate the incidence of de novo OAB symptoms after the procedure.
Main Methods:
- Prospective, observational study involving 63 adult patients undergoing flexible cystoscopy.
- OAB symptoms assessed using the OAB-V8 tool pre-procedure and on postoperative days 1 and 4.
- Patients categorized as OAB-negative (<8) or OAB-positive (≥8) based on scores.
Main Results:
- Mean OAB scores increased significantly on postoperative day 1 (p<0.01) but returned to baseline by day 4 (p=0.08).
- OAB positivity increased from 33.3% pre-procedure to 50.8% post-procedure, with 26.2% developing de novo symptoms.
- Age, gender, indication, and alpha-blocker use did not significantly impact OAB score changes.
Conclusions:
- Flexible cystoscopy can transiently exacerbate or trigger OAB symptoms.
- De novo OAB symptoms post-procedure are common but typically resolve.
- Findings can inform patient counseling and management strategies for OAB after cystoscopy.
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