Functional Magnetic Resonance Imaging Studies in Antisocial Personality Disorder: A Narrative Literature Review

Individuals with antisocial personality disorder (ASPD) are characterized by impulsive behavior and a lack of empathy, which can eventually lead to criminal behavior. In our narrative review, we are investigating the neurological differences in the function, structure, and connectivity of those with ASPD in comparison to those without, with a major focus on psychopathic cluster B populations of ASPD individuals. We reviewed 86 published articles, and five of these met the inclusion criteria for distinct psychopathic and non-psychopathic groups. After reviewing these sources, we found deficits in function and structure leading to a lack of empathy and adherence to social norms in individuals with ASPD. Currently, there are very few treatment options for those living with ASPD. It is our opinion that with a better understanding of the structural and functional differences in those with ASPD, we might see more efficacious treatment therapies for this population group in the medical community.