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Updated: Jun 18, 2025

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Published on: June 21, 2024
An Interesting Finding of Xanthogranulomatous Pyelonephritis Revealed Concomitant Incidental Squamous Cell Carcinoma
Malik Samardali1, Ibrahim Shanti1, Jehad Samardaly2
1Internal Medicine, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.
Abstract:
Squamous cell carcinoma, originating in the renal pelvis, is an infrequent form of kidney malignancy. The occurrence rate remains below 1% for all neoplasms in this specific area. Most of these carcinomas are moderately or poorly differentiated, and diagnosis typically occurs at an advanced stage. Xanthogranulomatous pyelonephritis is an uncommon form of severe chronic infection that affects the parenchyma of native kidneys. We present the case of a 34-year-old male with a history of end-stage renal disease secondary to recurrent pyelonephritis, which was incidentally diagnosed as renal squamous cell carcinoma (SCC).
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