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Prediabetes: A Benign Intermediate Stage or a Risk Factor in Itself?

Irfan G Mulla1, Ashish Anjankar2, Shilpa Pratinidhi3

  • 1Biochemistry, Datta Meghe Institute of Higher Education & Research (DMIHER), Wardha, IND.

Cureus
|July 29, 2024
PubMed

Insights

Prediabetes increases risks for serious health issues like cardiovascular events. Early screening and management of prediabetes can prevent its progression to diabetes and reduce future complications.

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Public Health

Background:

  • Prediabetes is characterized by elevated blood glucose levels, previously underestimated but now linked to significant health risks.
  • Recognized association with macrovascular and microvascular complications, including cardiovascular events, nephropathy, neuropathy, and retinopathy.

Purpose of the Study:

  • Advocate for early prediabetes identification through screening.
  • Highlight the importance of timely management strategies to prevent diabetes progression and associated complications.

Main Methods:

  • Review of current understanding of prediabetes.
  • Emphasis on screening protocols for early detection.
  • Discussion of available therapeutic interventions.

Main Results:

  • Prediabetes is not benign and carries substantial risks for long-term health complications.
  • Early detection allows for timely intervention to mitigate these risks.

Conclusions:

  • Screening for prediabetes is crucial for identifying at-risk individuals.
  • Implementing management strategies can retard progression to type 2 diabetes and prevent severe health outcomes.

Keywords:
hemoglobin a1c (hba1c)homeostatic model assessment for insulin resistance (homa-ir)insulin-like growth factor (igf)intermediateprediabetes risk

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