Related Experiment Video
Updated: Jun 18, 2025
Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Cardiac arrest and cardiogenic shock complicating ST-segment elevation myocardial infarction in China: A
Shao-Shuai Liu1, Juan Wang2, Hui-Qiong Tan3,4
1Department of Cardiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, Shandong, 266035, China.
Insights
Cardiac arrest (CA) and cardiogenic shock (CS) significantly increase 30-day mortality and adverse events in Chinese ST-segment elevation myocardial infarction (STEMI) patients. The combination of CA and CS poses the highest risk, underscoring the need for prompt intervention.
Area of Science:
- Cardiology
- Clinical Medicine
- Public Health
Background:
- Limited data exists on the combined impact of cardiac arrest (CA) and cardiogenic shock (CS) on Chinese patients with ST-segment elevation myocardial infarction (STEMI).
- Understanding these effects is crucial for improving prognosis in this high-risk population.
Purpose of the Study:
- To evaluate the clinical outcomes of STEMI patients experiencing CA and/or CS.
- To identify risk factors associated with CA or CS in STEMI patients.
Main Methods:
- A cohort study of 7468 consecutive STEMI patients in China.
- Patients were categorized into four groups: CA + CS, CA only, CS only, and No CA or CS.
- Cox proportional hazards regression analysis was used to assess 30-day all-cause death and major adverse cardiovascular events.
Main Results:
- Cardiac arrest (CA) and cardiogenic shock (CS) occurred in 4.4% and 5.0% of patients, respectively, with a 1.6% experiencing both.
- The incidence of 30-day mortality and major adverse cardiovascular events significantly increased across groups: No CA or CS, CS only, CA only, and CA + CS.
- Patients with both CA and CS faced the highest risk of all-cause death (HR 25.259) and major adverse cardiovascular events (HR 19.098) compared to those without CA or CS.
Conclusions:
- Approximately 11% of Chinese STEMI patients experienced CA, CS, or both.
- These conditions are independently associated with a substantially increased risk of 30-day mortality and major adverse cardiovascular events.
- The findings highlight the critical impact of CA and CS on STEMI prognosis in the Chinese population.
Background:
Data on the effect of cardiac arrest (CA), cardiogenic shock (CS), and their combination on the prognosis of Chinese patients with ST-segment elevation myocardial infarction (STEMI) are limited. The present study sought to evaluate the clinical outcomes of STEMI complicated by CA and CS, and to identify the risk factors for CA or CS.
Methods:
This study included 7468 consecutive patients with STEMI in China. The patients were divided into 4 groups (CA + CS, CA only, CS only, and No CA or CS). The endpoints were 30-day all-cause death and major adverse cardiovascular events. A Cox proportional hazards regression analysis was performed.
Results:
CA, CS, and their combination were noted in 332 (4.4 %), 377 (5.0 %), and 117 (1.6 %) among all patients. During the 30-day follow-up, 817 (10.9 %) all-cause deaths and 964 (12.9 %) major adverse cardiovascular events occurred, and the incidence of all-cause mortality (3.6 %, 62.3 %, 74.1 %, 83.3 %) and major adverse cardiovascular events (5.4 %, 67.1 %, 75.0 %, and 87.2 %) significantly increased in the No CA or CS, CS only, CA only, and CA + CS groups, respectively. In the multivariate Cox regression models, compared with the No CA or CS group, the CA + CS, CA, and CS-only groups were associated with an increased risk of all-cause death and major adverse cardiovascular events. Patients with CA + CS had the highest risk of all-cause death (hazard ratio [HR], 25.259 [95 % confidence interval (CI) 19.221-33.195]) and major adverse cardiovascular events (HR 19.098, 95%CI 14.797-24.648).
Conclusions:
CA, CS, and their combination were observed in approximately 11 % of Chinese patients with STEMI, and were associated with increased risk for 30-day mortality and major adverse cardiovascular events in Chinese patients with STEMI.
More Related Videos
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
05:26Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Related Concept Videos
01:24Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
01:26Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...