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Factors predicting the recurrence of atrial fibrillation after catheter ablation: A review

Degang Mo1, Mengmeng Wang2, Peng Zhang2

  • 1Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, 266011, China.

Heliyon
|July 29, 2024
PubMed

Insights

Identifying patients at high risk for atrial fibrillation (AF) recurrence after catheter ablation (CA) is crucial. This review covers predictors like fibrosis, inflammation, and genetic markers to improve patient outcomes.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) is a common cardiac arrhythmia.
  • Catheter ablation (CA) can restore sinus rhythm but recurrence is a clinical challenge.

Purpose of the Study:

  • To review current predictors of AF recurrence after CA.
  • To explore mechanisms underlying AF recurrence.
  • To aid researchers in understanding and predicting AF recurrence.

Main Methods:

  • Literature review of predictors for AF recurrence post-CA.
  • Summary of myocardial fibrosis markers.
  • Analysis of inflammatory markers, MicroRNAs, and Circular RNAs.
  • Inclusion of AF recurrence scores and imaging indicators.

Main Results:

  • Multiple predictors exist for AF recurrence, including biological markers and imaging.
  • Individual predictors have limitations; combined application may enhance predictive power.
  • Mechanisms involve patient history, inflammation, fibrosis, and genetic factors.

Conclusions:

  • Early identification of high-risk patients for AF recurrence is essential for improved prognosis.
  • Further research into combined predictors and underlying mechanisms is warranted.
  • This review provides a comprehensive overview of current AF recurrence predictors.

Keywords:
Atrial fibrillationCatheter ablationPredictPredictorsRecurrence

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