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Related Experiment Video

Updated: Jun 18, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Metachronous multifocal carcinoma: A case report.

Dan-Dan Wan1, Xiao-Ju Li2, Xing-Ru Wang3

  • 1School of Clinical Medicine, Qujing Medical College, Qujing 655000, Yunnan Province, China.

World Journal of Gastrointestinal Oncology
|July 29, 2024
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of simultaneous liver and colon cancer with a subsequent pancreatic tumor. Advanced treatments improved the patient's prognosis and survival period.

Keywords:
Case reportComprehensive diagnosis and treatmentHeterochronous pancreatic cancerMetachronous multifocal carcinomaMultiple primary carcinomas

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Multiple primary carcinomas (MPC) incidence varies globally, with rare occurrences of simultaneous multigenic cancers.
  • Duo-duplex carcinoma is most common; trio-duplex and above are rare.
  • No prior reports exist for simultaneous dual-origin liver and colon cancer with heterochronous pancreatic cancer.

Observation:

  • A unique case of multifocal carcinoma involving primary liver and colon cancer is presented.
  • The patient developed pancreatic cystadenocarcinoma two years post-surgery for initial cancers.
  • Advanced fluorescent laparoscopic techniques were employed for diagnosis and treatment.

Findings:

  • The patient received standardized immunotherapy, targeted therapy, and chemotherapy.
  • Aggressive treatment led to a better prognosis and extended survival.
  • This case highlights a rare combination of simultaneous and heterochronous primary cancers.

Implications:

  • Clarifying the nature of multiple primary carcinomas (MPC) is crucial for improved diagnosis and treatment strategies.
  • Advanced surgical techniques and multimodal therapies can enhance outcomes in complex oncological cases.
  • Further research is needed to understand the etiology and optimal management of rare MPC presentations.