Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

298
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
298
Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genital Herpes Simplex Virus (HSV) Infection During Pregnancy - Recommendations of the Working Group on Obstetrics and Prenatal Medicine (AGG - Section on Maternal Disorders).

Geburtshilfe und Frauenheilkunde·2026
Same author

Diagnostic yield of chromosomal microarray analysis and exome sequencing in fetuses with central nervous system anomalies, with long-term follow-up: a single-center study over a 17-year period.

Archives of gynecology and obstetrics·2026
Same author

Predictive value of gB2 antibodies for maternal-fetal transmission after primary cytomegalovirus infection treated with valacyclovir.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
Same author

Impact of a new image enhancement technology on the biometric measurements in pregnancy.

Archives of gynecology and obstetrics·2026
Same author

Diagnosis and Therapy of Endometriosis. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025).

Geburtshilfe und Frauenheilkunde·2026
Same author

Transplacental Infection: Frequency, Testing, and Treatment.

Deutsches Arzteblatt international·2026

Related Experiment Video

Updated: Jun 18, 2025

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.4K

Prenatal parvovirus B19 infection.

Karl Oliver Kagan1, Markus Hoopmann2, Annegret Geipel3

  • 1Department of Obstetrics and Gynaecology, University Hospital Tuebingen, Calwerstrasse 7, 72076, Tuebingen, Germany. KOKagan@gmx.de.

Archives of Gynecology and Obstetrics
|July 29, 2024
PubMed
Summary
This summary is machine-generated.

Parvovirus B19 infection during pregnancy can lead to fetal complications like anemia and hydrops fetalis. Early monitoring and intervention, including intrauterine transfusions, are crucial for managing severe cases.

Keywords:
AnemiaHydropsInfectionParvovirus B19Prenatal

More Related Videos

Neurogenesis Using P19 Embryonal Carcinoma Cells
07:46

Neurogenesis Using P19 Embryonal Carcinoma Cells

Published on: April 27, 2019

10.8K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.3K

Related Experiment Videos

Last Updated: Jun 18, 2025

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.4K
Neurogenesis Using P19 Embryonal Carcinoma Cells
07:46

Neurogenesis Using P19 Embryonal Carcinoma Cells

Published on: April 27, 2019

10.8K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.3K

Area of Science:

  • Virology
  • Obstetrics
  • Pediatrics

Background:

  • Parvovirus B19 (B19V) causes fifth disease, typically mild in children.
  • Pregnant women not immune to B19V are at risk for primary infection.
  • B19V infection in pregnancy poses risks including fetal anemia, hydrops fetalis, miscarriage, and intrauterine fetal death.

Purpose of the Study:

  • To provide a comprehensive overview of B19V infection in pregnancy.
  • To detail the epidemiology, pathogenesis, clinical features, diagnosis, and management of B19V during gestation.

Main Methods:

  • Review of existing literature on B19V infection in pregnancy.
  • Discussion of diagnostic methods including ultrasound and Doppler studies.
  • Outline of management strategies, including fetal blood sampling and intrauterine transfusions.

Main Results:

  • Maternal-fetal transmission occurs in 30-50% of primary B19V infections during pregnancy.
  • Risk of fetal anemia or hydrops is 3-4% overall, increasing to 6-7% if infection occurs before 20 weeks gestation.
  • Fetal monitoring involves ultrasounds and Doppler measurements; intrauterine transfusions are used for severe fetal anemia.

Conclusions:

  • B19V infection during pregnancy requires careful monitoring due to potential severe fetal outcomes.
  • Timely diagnosis and intervention, such as intrauterine transfusions, can improve fetal prognosis.
  • Understanding B19V's impact is vital for obstetric and pediatric care providers.