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Shapiro's syndrome: episodic hypothermic hyperhidrosis
Deepa Avadhani1, Lakshmi Narasimhan Ranganathan2, Chandramouleeswaran Venkataraman3
1Department of Neurology, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, Tamil Nadu, India doctoravadhanideepa@gmail.com.
Abstract:
SummaryShapiro's syndrome is a rare neurological disease. The triad of Shapiro's syndrome includes episodes of hyperhidrosis, hypothermia and complete/partial agenesis of the corpus callosum. We report a case of a young male who had episodic chills, increased sweating and fatigue. During these episodes, he was found to have bradycardia, hypotension and hypothermia. Clinical and neurological examinations were unremarkable. The MRI of the brain revealed agenesis of the corpus callosum. There was a good response to carbamazepine therapy.
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