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Published on: October 16, 2021
Present and Future Surgical Options for Tricuspid Regurgitation
Ana Paula Tagliari1,2, Maurizio Taramasso3
1Instituto de Ciências Biológicas e da Saúde, Universidade Federal do Rio Grande do Sul, 90046-900 Porto Alegre, Brazil.
Tricuspid regurgitation (TR) is increasingly recognized for its significant impact. This review explores current and future surgical management strategies for severe TR, including indications and clinical trials.
Area of Science:
- Cardiology
- Cardiac Surgery
- Clinical Medicine
Background:
- Tricuspid regurgitation (TR) was historically underestimated but is now recognized for its significant impact on patient outcomes.
- Current guidelines offer Class I indications for surgical intervention in limited scenarios of severe TR.
- Advances in understanding TR's prognosis necessitate a re-evaluation of management strategies.
Purpose of the Study:
- To review the current landscape of surgical tricuspid regurgitation management.
- To examine the prognosis, indications, and outcomes associated with surgical TR intervention.
- To provide an overview of ongoing and future clinical trials in surgical TR management.
Main Methods:
- Literature review of current guidelines and clinical evidence.
- Analysis of prognostic factors and surgical outcomes in tricuspid regurgitation.
- Survey of completed, ongoing, and planned clinical trials related to surgical TR.
Main Results:
- Severe tricuspid regurgitation significantly impacts short- and long-term patient follow-up.
- Surgical intervention is the standard for severe TR but indications are currently restrictive.
- Numerous clinical trials are investigating expanded indications and novel approaches for surgical TR.
Conclusions:
- The management of tricuspid regurgitation requires a nuanced approach considering evolving evidence.
- Future research and clinical trials are crucial for refining surgical indications and improving outcomes.
- Optimizing surgical management of TR is essential for improving patient prognosis.
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