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Updated: Jun 18, 2025

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Published on: August 16, 2021
Update on Percutaneous Treatment for HFrEF: A Great Armamentarium for a Poor Ventricular Function
Antonio Sisinni1, Matteo Casenghi2, Antonio Popolo Rubbio1
1Clinical and Interventional Cardiology Department, IRCCS Policlinico San Donato, 20097 San Donato Milanese, Italy.
This review covers transcatheter devices for heart failure with reduced ejection fraction (HFrEF). It focuses on clinical selection criteria for these non-pharmacological treatments in symptomatic patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Pharmacological therapy is standard for heart failure with reduced ejection fraction (HFrEF).
- Some heart failure (HF) patients have specific phenotypes, like valvular heart disease, requiring non-pharmacological interventions.
- High-level patient care necessitates addressing prognostic relevance through advanced treatments.
Purpose of the Study:
- To provide a clinical overview of transcatheter devices for HFrEF.
- To focus on the selection criteria for these devices in interventional cardiology.
- To review current data on non-pharmacological treatment options for HF phenotypes.
Main Methods:
- Review of clinical data on transcatheter devices.
- Analysis of selection criteria for interventional cardiology procedures.
- Focus on symptomatic HF patients with specific phenotypes.
Main Results:
- Transcatheter devices offer alternative treatment options for select HFrEF patients.
- Clinical and anatomical criteria are crucial for device selection.
- Percutaneous techniques are evolving for HF management.
Conclusions:
- Transcatheter devices are an important part of the interventional cardiologist's toolkit for HFrEF.
- Careful patient selection based on clinical and anatomical factors is essential for successful outcomes.
- This review highlights the growing role of percutaneous interventions in managing complex HF cases.
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