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Updated: May 6, 2026

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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
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Choosing Appropriate Candidates for Left Atrial Appendage Occlusion
Chengxiang Zhang1, Hao Lu1, Yuansong Zhu2
1Department of General Medicine, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Reviews in Cardiovascular Medicine
|July 30, 2024
Summary
Atrial fibrillation (AF) stroke risk can be managed with left atrial appendage occlusion (LAAO). This review details patient selection criteria for LAAO, offering a crucial alternative to oral anticoagulation.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Cardiology
Background:
- Atrial fibrillation (AF) is a common arrhythmia, increasing stroke risk by up to fivefold.
- Oral anticoagulation is standard for stroke prevention in nonvalvular AF.
- Left atrial appendage occlusion (LAAO) offers an alternative for patients intolerant to anticoagulation.
Purpose of the Study:
- To review current recommendations for patient selection in LAAO procedures.
- To identify key factors for pre- and post-procedural evaluation in LAAO.
- To discuss advancements in LAAO patient selection.
Main Methods:
- Literature review of current guidelines and clinical studies.
- Analysis of factors influencing LAAO candidacy.
- Discussion of emerging trends in LAAO patient selection.
Main Results:
- Patient selection for LAAO involves a complex assessment of clinical factors.
- No single guideline universally dictates LAAO candidacy.
- Ongoing research aims to refine selection criteria and improve outcomes.
Conclusions:
- Left atrial appendage occlusion is a valuable stroke prevention strategy in select AF patients.
- Comprehensive patient evaluation is critical for successful LAAO.
- Future advancements will likely enhance the precision of LAAO candidate selection.

