[Medical treatment of soft-tissue sarcomas in adults]

Soft tissue sarcomas are rare tumors. There is a lot of histologic varieties but the natural history and the prognosis are very similar. Surgery remains the first step of the treatment policy. Radiotherapy, given additionally, can prevent local relapse. Till now, chemotherapy was given to patientes with advanced diseases. Except doxorubicine and ifosfamide much drugs act poorly in the solft tissue sarcomas. CYVADIC is the best combination available. One randomized study has established the value of adjuvant chemotherapy in soft tissue sarcomas of the extremities. The real place of chemotherapy, probably will be in the next years, beside surgery and radiotherapy, in a multidisciplinary combined approach.