Performance of ultrasound guidance for vacuum-assisted biopsy of breast microcalcifications without associated mass

•The accuracy of ultrasound (US)-guided biopsies of suspicious microcalcifications without mass is similar, or even better than results published in literature with stereotactic-guided biopsies.•When the microcalcifications are visible on ultrasound, there is no loss of chance in performing the biopsy under ultrasound guidance rather than under stereotactic guidance.•US guidance allows access to difficult areas for stereotactic, increases the comfort of the patient, avoids compression and irradiation.