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Clinical Effect of the Modified Morrow Septal Myectomy Procedure for Biventricular Hypertrophic Cardiomyopathy

Tong Tan1,2, Wei Zhu1, Jianrui Ma1

  • 1Department of Cardiovascular Surgery, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510000 Guangzhou, Guangdong, China.

Reviews in Cardiovascular Medicine
|July 30, 2024
PubMed

Insights

Modified septal myectomy effectively treats biventricular hypertrophic cardiomyopathy (BHCM), improving outcomes. This surgery safely relieves biventricular outflow tract obstruction (BVOTO) and reduces septum thickness with minimal complications.

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Medical Devices

Background:

  • Right ventricular involvement is rare in hypertrophic cardiomyopathy.
  • Biventricular hypertrophic cardiomyopathy (BHCM) presents unique challenges.
  • Limited literature explores surgical outcomes for BHCM.

Purpose of the Study:

  • Evaluate clinical outcomes of modified septal myectomy in BHCM patients.
  • Assess the safety and efficacy of treating biventricular outflow tract obstruction (BVOTO).
  • Explore the role of 3D printing in surgical planning for BHCM.

Main Methods:

  • Retrospective cohort study of 12 BHCM patients (2019-2023).
  • All patients underwent modified septal myectomy.
  • Collected clinical and echocardiographic data, including outflow tract gradients and septum thickness.

Main Results:

  • Significant reduction in interventricular septum thickness (21.0 mm to 14.5 mm, p < 0.001).
  • Successful relief of BVOTO in 5 patients (41.7%).
  • No severe complications, including septal perforation or heart block; no deaths or reoperations during follow-up.

Conclusions:

  • Modified septal myectomy is the gold standard for BHCM, enhancing quality of life.
  • Septal myectomy safely and effectively addresses BVOTO in selected patients.
  • 3D printing aids surgical precision in complex BHCM cases.
Abstract

Keywords:
3D printingbiventricular hypertrophic cardiomyopathybiventricular outflow tract obstructionclinical analysishypertrophic obstructive cardiomyopathymodified septal myectomyventricular outflow tract obstruction

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