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Updated: Jul 27, 2026
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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
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Insufficient Ablation is Associated with Atrial Fibrillation Recurrence after Combining Ablation and Left Atrial
Xueyan Ding1, Yao Zhao2, Shaohua Dong2
1Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 310016 Hangzhou, Zhejiang, China.
Reviews in Cardiovascular Medicine
|July 30, 2024
Summary
Insufficient ablation during combined catheter ablation and left atrial appendage closure increases atrial fibrillation recurrence. Correcting ablation gaps significantly reduces recurrence, highlighting the importance of sufficient pulmonary vein antrum ablation.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Combined catheter ablation (CA) and left atrial appendage closure (LAAC) is a treatment for atrial fibrillation (AF).
- Concerns exist that LAAC may increase AF recurrence risk.
- This study addresses the impact of ablation quality on AF recurrence post-hybrid procedures.
Purpose of the Study:
- To investigate the influence of insufficient ablation on AF recurrence after combined CA and LAAC.
- To determine if correcting ablation gaps impacts AF recurrence rates.
Main Methods:
- A retrospective review of 107 patients undergoing combined CA and LAAC (combined group).
- Propensity score matching to compare with 107 patients undergoing CA alone (ablation group).
- Prospective enrollment of 107 patients after correcting ablation insufficiency, with follow-up using monitoring devices and echocardiography.
Main Results:
- The combined group showed a higher AF recurrence rate (29.9%) compared to the ablation group (15.9%) over ~540 days.
- Procedure duration was not significantly increased by adding LAAC after CA.
- Correcting insufficient ablation led to a significant decrease in AF recurrence over ~420 days.
Conclusions:
- Insufficient ablation is a significant factor in AF recurrence after hybrid CA and LAAC procedures.
- Intentional correction of ablation gaps, particularly in the pulmonary vein antrum, is crucial.
- Optimizing ablation technique can improve outcomes for patients undergoing combined AF treatments.
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