Japanese clinical practice guidelines for prostate cancer 2023

Area of Science:

• Urology
• Oncology
• Evidence-Based Medicine

Background:

• The Japanese Clinical Practice Guidelines for Prostate Cancer were revised for their fourth edition.
• Revision involved multiple academic societies and patient groups, adhering to the Minds Manual for Guideline Development.

Purpose of the Study:

• To provide updated, evidence-based recommendations for prostate cancer management.
• To incorporate systematic reviews into the guideline development process.

Main Methods:

• Systematic reviews (SRs) were conducted for 14 clinical questions (CQs).
• Recommendations were finalized based on SR results and voting by the guideline development group.
• Five algorithms were developed based on the review findings.

Main Results:

• Recommendations for 14 clinical questions were established using qualitative SRs.
• General statements cover topics not addressed by SRs, including findings post-2016.
• The guidelines integrate new evidence and methodologies for prostate cancer care.

Conclusions:

• The 2023 guidelines represent a significant update in prostate cancer clinical practice.
• The adoption of SRs enhances the evidence base for recommendations.
• These guidelines aim to improve patient outcomes through standardized, evidence-based care.