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Updated: Jun 18, 2025
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Technique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts
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Liver Transplantation: A Test of Cellular Physiology, Preservation, and Injury
B Martins1, J Mossemann1, F Aguilar1
1Cell Biology Program, Hospital for Sick Children, Toronto, Ontario, Canada.
Physiology (Bethesda, Md.)
|July 30, 2024
Abstract:
Liver transplantation has evolved into a mature clinical field, but scarcity of usable organs poses a unique challenge. Expanding the donor pool requires novel approaches for protecting hepatic physiology and cellular homeostasis. Here we define hepatocellular injury during transplantation, with an emphasis on modifiable cell death pathways as future therapeutics.
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