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Biosafety, biosecurity, and bioethics.

David B Resnik1

  • 1National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, Research Triangle Park, NC, 27709, USA. resnikd@niehs.nih.gov.

Monash Bioethics Review
|July 30, 2024
PubMed
Summary
This summary is machine-generated.

Biosafety in biomedical sciences involves critical ethical considerations beyond technical aspects. This review examines historical events and ethical issues in risk assessment, management, and distribution, advocating for bioethics integration.

Keywords:
BioethicsBiosafetyBiosecurityDemocracyGain of function researchRisk

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Area of Science:

  • Biomedical Sciences
  • Bioethics
  • Public Health Policy

Background:

  • The COVID-19 pandemic underscored the critical role of biosafety in biomedical research.
  • Biosafety is often perceived as a technical issue, overlooking its significant ethical dimensions.
  • Existing scientific and bioethics literature inadequately addresses the ethical challenges in biosafety.

Purpose of the Study:

  • To review historical milestones in biosafety and biosecurity.
  • To explore ethical concerns related to biosafety's risk assessment, management, and distribution.
  • To propose integrating bioethics into biosafety practices, education, and policy.

Main Methods:

  • Historical review of pivotal biosafety and biosecurity events.
  • Ethical analysis of key biosafety topics: risk assessment, management, and distribution.
  • Discussion of democratic governance in biosafety oversight.

Main Results:

  • Biosafety encompasses complex ethical issues not typically covered in technical or bioethics literature.
  • Risk assessment, management, and distribution present significant ethical challenges.
  • Democratic governance models can enhance biosafety oversight.

Conclusions:

  • Biosafety requires a deeper ethical examination, integrating philosophical and humanities perspectives.
  • Bioethics should be incorporated into biosafety practice, education, and policy development.
  • Strengthening democratic governance is crucial for effective biosafety oversight.